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Ginkgo leaf extract and dipyridamole injection for chronic ...

Ginkgo leaf extract and dipyridamole injection (GLED), a kind of Chinese herbal medicine preparation, has been considered as a promising supplementary treatment for chronic cor pulmonale (CCP). Although an analysis of the published literature has been performed, the exact effects and safety of GLED have yet to be systematically investigated.

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Ginkgo biloba L. Leaf Extract Protects HepG2 Cells Against ...

Ginkgo biloba leaf extract produced dose-dependent cytotoxicity (IC 50 = 540.8 ± 40.5 µg/mL at 24 h exposure), and short incubations (1 h) produced basal and oxidative DNA damage (>750 and 1500 µg/mL, respectively).

Potential interaction of Ginkgo biloba leaf with ...

Abstract. Some writers hold the view that the combination of Ginkgo biloba with anticoagulant or antiplatelet drugs represents a serious health risk. Such concerns are largely based on the assumption that Ginkgo has clinically relevant antiplatelet activity, as well as accounts of bleeding episodes associated with Ginkgo consumption. To investigate whether these bleeding episodes have a ...

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Ginkgo biloba leaf (GBL) is known as a potential source of bioactive flavonoids, such as quercetin, arresting the neuronal soluble N -ethylmaleimide-sensitive factor attachment protein receptor (SNARE)-zippering.

Ginkgo: Uses, Side Effects, Interactions, Dosage, and Warning

In manufacturing, ginkgo leaf extract is used in cosmetics. In foods, roasted ginkgo seed, which has the pulp removed, is an edible delicacy in Japan and China. How does it work? Ginkgo seems to...

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Ginkgo biloba leaf extract (EGb 761) is one of the highest selling herbal medicinal products in the world. Quercetin, 2- (3, 4-dihyroxyphenyl)-3, 5, 7-trihyroxy-4H-chromen-4-one, is a flavonoid in...

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Treatment of dementia and mild cognitive impairment with ...

EGb 761 ® is a dry extract from Ginkgo biloba leaves, adjusted to 22.0%‐27.0% ginkgo flavonoids and 5.0%‐7.0% terpene lactones consisting of 2.8%‐3.4% ginkgolides A, B, and C, and 2.6%‐3.2% bilobalide, and containing less than 5 ppm ginkgolic acids.

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Ginkgo biloba leaf extract produced dose-dependent cytotoxicity (IC 50 = 540.8 ± 40.5 µg/mL at 24 h exposure), and short incubations (1 h) produced basal and oxidative DNA damage (>750 and 1500 µg/mL, respectively).

(PDF) Ginkgo Biloba - researchgate.net

Abstract and Figures Ginkgo biloba is a commonly used herbal supplement in the United States. We describe a 63-year-old man with a significant ventricular ectopic burden (32.7%) that was refractory...

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Abstract. The present study investigated the effects of Ginkgo biloba leaf extract (GBE50) on lipopolysaccharide (LPS) induced Toll-like receptor 4 (TLR4) /nuclear factor-κB (NF-κB) signaling pathway and its effects on angiotensinogen (ATG) and AT 1a receptor, so as to explore the mechanism of GBE50 in prevention and treatment of left ventricular remodeling. In vitro cultured neonatal rat ...

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Anti-melanogenic effect of the aqueous ethanol extract of ...

Ginkgo biloba leaf extract (GLE) shows diverse biological effects, and it is used as an ingredient in some skincare products. GLE and a few purified compounds are known to inhibit melanogenesis. However, there are very few reports on the molecular mechanisms underlying the regulation of melanogenesis by GLE.

Dietary Ginkgo biloba leaf extract alters immune-related ...

Abstract. Ginkgo biloba leaf is widely used in traditional medicine in China. The present study aimed to illustrate the effects of dietary Ginkgo biloba leaf extract (GBLE) on growth performance and immune responses in common carp infected by Aeromonas hydrophila. Six different diets either not treated (control) or treated with 0.5, 1, 2, 5 and 10 g/kg of GBLE were designed to feed the fishes ...

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Ginkgo biloba leaf extract induces DNA damage by ...

Abstract. Ginkgo biloba leaf extract has been shown to increase the incidence in liver tumors in mice in a 2-year bioassay conducted by the National Toxicology Program. In this study, the DNA damaging effects of Ginkgo biloba leaf extract and many of its constituents were evaluated in human hepatic HepG2 cells and the underlying mechanism was determined. A molecular docking study revealed that ...

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The neuroprotective properties of the Ginkgo biloba leaf ...

Ginkgo biloba (Ginkgoaceae) is an ancient Chinese tree which has been cultivated and held sacred for its health-promoting properties. There is substantial experimental evidence to support the view that Ginkgo biloba extracts have neuroprotective properties under conditions such as hypoxia/ischemia, seizure activity and peripheral nerve damage. Research on the biochemical effects of Ginkgo ...

Ginkgo folium | European Medicines Agency

Ginkgo leaf medicines should only be used in adults. If symptoms of dementia do not improve after 3 months or if symptoms worsen during the treatment, a doctor should be consulted. For the treatment of minor circulation problems, a doctor or a qualified healthcare practitioner should be consulted if symptoms persist for longer than 2 weeks. Detailed instructions on how to take ginkgo leaf ...

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Variation in Ginkgo biloba L. leaf characters across a ...

Abstract. Fossil leaves assigned to the genus Ginkgo are increasingly being used to reconstruct Mesozoic and Tertiary environments based on their stomatal and carbon isotopic characteristics. We sought to provide a more secure basis for understanding variations seen in the plant fossil record by determining the natural variability of these properties of sun and shade leaf morphotypes of Ginkgo ...

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Abstract. The aim of this study was to prove whether Ginkgo biloba food supplements on the European market comply with pharmaceutical quality, and whether their composition satisfies the European Pharmacopoeia criteria. Medicinal products containing a standardised Ginkgo leaf extract are used for the improvement of cognitive impairment and quality of life in mild dementia.

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Ginkgo Leaf Extract and Dipyridamole Injection as Adjuvant ...

Abstract. Objective. To provide information about the effectiveness and safety of Ginkgo Leaf Extract and Dipyridamole Injection (GD) as one adjuvant therapy for treating angina pectoris (AP) and to evaluate the relevant randomized controlled trials (RCTs) with meta-analysis. Methods . RCTs concerning AP treated by GD were searched in China Biology Medicine Disc (SinoMed), PubMed, the China ...

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Ginkgo Biloba | JACC: Case Reports

Ginkgo biloba is a commonly used herbal supplement in the United States. We describe a 63-year-old man with a significant ventricular ectopic burden (32.7%) that was refractory to metoprolol tartrate (41.7%) and resolved (<1%) when Ginkgo was discontinued. This case supports a potential proarrhythmic side-effect of over-the-counter Ginkgo leaf extract.

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The present invention discloses a kind of method of extracting flavones in ginkgo leaf, relate to extraction process technology field, comprise following extraction step: dry Folium Ginkgo is pulverized, then will in the warm water of 40 DEG C-60 DEG C of Ginkgo Leaf immersions, carry out lixiviate, in lixiviate, solid-to-liquid ratio is 1:10(W/V), extraction time is 3 hours, extracts three ...

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Ginkgo biloba leaf extract (EGb 761®) and its specific ...

Ginkgo biloba leaf extract (EGb 761®) and its specific acylated flavonol constituents increase dopamine and acetylcholine levels in the rat medial prefrontal cortex: possible implications for the cognitive enhancing properties of EGb 761® - Volume 24 Issue S1 - J. Kehr, S. Yoshitake, S. Ijiri, E. Koch, M. Nöldner, T. Yoshitake

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